Pipecolic acid

Pipecolic acid
IUPAC name

piperidine-2-carboxylic acid
Identifiers
CAS number 3105-95-1 Y
PubChem 849
MeSH pipecolic+acid
Jmol-3D images Image 1
Properties
Molecular formula C6H11NO2
Molar mass 129.15704
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pipecolic acid (piperidine-2-carboxylic acid) is a small organic molecule which accumulates in pipecolic acidemia. It is the carboxylic acid of piperidine.

It can be associated with some forms of epilepsy.[1]

CRYM, a taxon-specific crystallin protein that also binds thyroid hormones, is involved in the pipecolic acid pathway.

Pipecolic acid was identified in the Murchison meteorite.[2]

References

  1. ^ Plecko B, Hikel C, Korenke GC, et al. (2005). "Pipecolic acid as a diagnostic marker of pyridoxine-dependent epilepsy". Neuropediatrics 36 (3): 200–5. doi:10.1055/s-2005-865727. PMID 15944906. 
  2. ^ Kvenholden, Keith A.; Lawless, James G.; Ponnamperuma, Cyril (February 1971). "Nonprotein Amino Acids in the Murchison Meteorite". Proceedings of the National Academy of Sciences 68 (2): 486–490. doi:10.1073/pnas.68.2.486. PMC 388966. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=388966. Retrieved August 4, 2011. 

See also